Knowledge is power, use it wisely!
The Ucar Lab at Jackson Laboratory for Genomic Medicine studies the dynamics of epigenetic regulation of gene expression in human cells to uncover how these patterns are disrupted with aging in immune cells and with Type 2 Diabetes in pancreatic islet cells. We develop computational pipelines and methods to analyze and integrate diverse genomics data from human cells.
Our GitHub page Our JAX Web Page
See our work on “genomics signatures of immune system and aging”, “systems biology and immunology” as well as “Functional genomics in Type-2-Diabetes”.
We have developped computational tools for doublet detetion on snATAC-seq data, detecting unwanted heterogeneity in single-cell RNA-seq datasets, an enrichment test for TF footprinting analyses and more..!
We have the greatest team of scientest coming both from computational and biological backgrounds!